{"id":1623,"date":"2026-09-25T19:40:49","date_gmt":"2026-09-25T23:40:49","guid":{"rendered":"https:\/\/canasanta.ca\/?p=1623"},"modified":"2026-09-25T19:40:49","modified_gmt":"2026-09-25T23:40:49","slug":"crispr-creates-blood-resistant-to-cancer-attacks","status":"publish","type":"post","link":"https:\/\/canasanta.ca\/en\/al-dia\/crispr-crea-sangre-resistente-al-ataque-contra-el-cancer\/","title":{"rendered":"CRISPR CREATES BLOOD RESISTANT TO CANCER TREATMENT"},"content":{"rendered":"<p>The idea sounds like something out of a movie: <strong>modify healthy blood so that it can survive an attack designed to destroy cancer<\/strong>. But that is precisely what researchers are trying to achieve by using <em>CRISPR<\/em>.<\/p>\n<p>The problem lies in a protein called <em><strong>CD33<\/strong><\/em>. It is found in the malignant cells of certain blood cancers, particularly acute myeloid leukemia, but it is also present in normal blood cells. This creates a major challenge: a treatment that is aggressive enough against CD33 may attack the cancer, but it may also destroy cells that the patient needs.<\/p>\n<p>The strategy is to change the rules of the game first.<\/p>\n<p>The scientists modified it using <em>CRISPR<\/em> blood stem cells from donors for <strong>delete <em>CD33<\/em><\/strong>. They were then transplanted into patients with the aim of rebuilding a blood system in which the healthy cells would no longer express that target.<\/p>\n<p>If those modified cells manage to establish themselves successfully, the next step is particularly promising: using CD33-targeted therapies to attack the cancer cells while sparing the new blood cells.<\/p>\n<p>The important thing is that <strong>This has already affected humans<\/strong>. The clinical trial included 30 patients and showed that the edited cells could be transplanted and produce blood cells without <em>CD33<\/em>. It is an initial demonstration that the strategy is biologically possible.<\/p>\n<p>That doesn't mean that <em>CRISPR<\/em> It has not yet been shown to create \u201ccancer-immune\u201d blood, nor is there a new cure. The study is in its early stages, and it remains to be seen to what extent this strategy improves survival and can be safely used on a larger scale.<\/p>\n<p>But this concept challenges the traditional approach to treatment: <strong>Instead of simply looking for a way to attack cancer without harming healthy cells, scientists are trying to first modify the healthy cells so that they can withstand a much more precise attack on the tumor.<\/strong><\/p>\n<p>And that difference could usher in a new era in the fight against some of the most difficult-to-treat blood cancers.<\/p>","protected":false},"excerpt":{"rendered":"<p>La idea parece sacada de una pel\u00edcula: modificar la sangre sana para que sobreviva a un ataque dise\u00f1ado para destruir el c\u00e1ncer. Pero eso es precisamente lo que investigadores est\u00e1n intentando conseguir utilizando CRISPR. El problema est\u00e1 en una prote\u00edna llamada CD33. Aparece en las c\u00e9lulas malignas de algunos c\u00e1nceres de la sangre, especialmente la [&hellip;]<\/p>\n","protected":false},"author":284226809,"featured_media":1627,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_wpcom_ai_launchpad_first_post":false,"_jetpack_hide_featured_image":false,"_jetpack_featured_image_duplicate_dismissed":0,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[33205457,33206009,2127],"tags":[33206011,33206104,33206050,33206106,33206103,33206105,33206018,33205938,33206013,33206107],"class_list":["post-1623","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-al-dia","category-investigacion","category-salud","tag-cancer","tag-cancer-de-sangre","tag-celulas-madre","tag-cd33","tag-crispr","tag-edicion-genetica","tag-leucemia","tag-medicina","tag-oncologia","tag-terapia-genetica"],"acf":{"introduccion":"Parece ciencia ficci\u00f3n, pero ya se est\u00e1 probando en seres humanos. Cient\u00edficos modificaron c\u00e9lulas madre con CRISPR para quitarles una mol\u00e9cula que tambi\u00e9n utilizan ciertos c\u00e1nceres de la sangre como blanco, con una idea tan radical como prometedora: <strong>proteger las c\u00e9lulas sanas mientras el tratamiento ataca al c\u00e1ncer con mayor precisi\u00f3n<\/strong>. El ensayo incluy\u00f3 a 30 pacientes y abre una nueva estrategia contra leucemias y otros c\u00e1nceres sangu\u00edneos dif\u00edciles de tratar. No es todav\u00eda una cura, pero podr\u00eda cambiar la forma en que se combate la enfermedad.","fuentes_y_referencias":"","autor":[748]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.1 (Yoast SEO v28.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>CRISPR CREA SANGRE RESISTENTE AL ATAQUE CONTRA EL C\u00c1NCER - Ca\u00f1asanta<\/title>\n<meta name=\"description\" content=\"Cient\u00edficos modifican c\u00e9lulas madre con CRISPR para proteger c\u00e9lulas sangu\u00edneas sanas mientras tratamientos dirigidos atacan determinados c\u00e1nceres de la sangre.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/canasanta.ca\/en\/daily\/crispr-creates-blood-resistant-to-cancer-attacks\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CRISPR CREA SANGRE RESISTENTE AL ATAQUE CONTRA EL C\u00c1NCER\" \/>\n<meta property=\"og:description\" content=\"Cient\u00edficos modifican c\u00e9lulas madre con CRISPR para proteger c\u00e9lulas sangu\u00edneas sanas mientras tratamientos dirigidos atacan determinados c\u00e1nceres de la sangre.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/canasanta.ca\/en\/daily\/crispr-creates-blood-resistant-to-cancer-attacks\/\" \/>\n<meta property=\"og:site_name\" content=\"Ca\u00f1asanta\" \/>\n<meta property=\"article:published_time\" content=\"2026-09-25T23:40:49+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/i0.wp.com\/canasanta.ca\/wp-content\/uploads\/2026\/09\/CS_BLOODcells_0001.jpg?resize=1200,630&quality=85&strip=all&ssl=1\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ca\u00f1asanta\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ca\u00f1asanta\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/canasanta.ca\\\/al-dia\\\/crispr-crea-sangre-resistente-al-ataque-contra-el-cancer\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/canasanta.ca\\\/al-dia\\\/crispr-crea-sangre-resistente-al-ataque-contra-el-cancer\\\/\"},\"author\":{\"name\":\"Ca\u00f1asanta\",\"@id\":\"https:\\\/\\\/canasanta.ca\\\/#\\\/schema\\\/person\\\/21421a3c6f1733be6c5c590190fd8e93\"},\"headline\":\"CRISPR CREA SANGRE RESISTENTE AL ATAQUE CONTRA EL C\u00c1NCER\",\"datePublished\":\"2026-09-25T23:40:49+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/canasanta.ca\\\/al-dia\\\/crispr-crea-sangre-resistente-al-ataque-contra-el-cancer\\\/\"},\"wordCount\":373,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/canasanta.ca\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/canasanta.ca\\\/al-dia\\\/crispr-crea-sangre-resistente-al-ataque-contra-el-cancer\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/i0.wp.com\\\/canasanta.ca\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/CS_BLOODcells_0001.jpg?fit=1200%2C631&quality=82&strip=all&ssl=1\",\"keywords\":[\"c\u00e1ncer\",\"c\u00e1ncer de sangre\",\"c\u00e9lulas madre\",\"CD33\",\"CRISPR\",\"edici\u00f3n gen\u00e9tica\",\"leucemia\",\"medicina\",\"oncolog\u00eda\",\"terapia gen\u00e9tica\"],\"articleSection\":[\"AL D\u00cdA!\",\"Investigaci\u00f3n\",\"Salud\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/canasanta.ca\\\/al-dia\\\/crispr-crea-sangre-resistente-al-ataque-contra-el-cancer\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/canasanta.ca\\\/al-dia\\\/crispr-crea-sangre-resistente-al-ataque-contra-el-cancer\\\/\",\"url\":\"https:\\\/\\\/canasanta.ca\\\/al-dia\\\/crispr-crea-sangre-resistente-al-ataque-contra-el-cancer\\\/\",\"name\":\"CRISPR CREA SANGRE RESISTENTE AL ATAQUE CONTRA EL C\u00c1NCER - 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